ISSN 2226-6976 (Print)
ISSN 2414-9640 (Online)

Plasmacytoma as a secondary lesion in HIV infection. A clinical case of combined severe secondary diseases

Mikhailova N.R., Mikhailovsky A.M., Plastamak O.N., Kalinina T.N., Skorovarova N.I., Nuriakhmetova O.V., Ermak T.N.

1) Orenburg State Medical University, Ministry of Health of the Russian Federation, Orenburg, Russia; 2) Orenburg Regional Clinical Anti-Tuberculosis Dispensary, Orenburg, Russia; 3) Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia
A case of solitary plasmacytoma with extensive lesions of the maxillofacial region in combination with a tuberculous process in a patient with HIV infection is presented. Antitumor therapy led to aggravation of immunodeficiency, which contributed to the development of tuberculosis with extensive drug resistance, a long course of the disease with an unfavorable prognosis.

Keywords

HIV infection
solitary plasmacytoma
tuberculosis

References

1. Feller L., White J., Wood N.H, Bouckaert M., Lemmer J., Raubenheimer E.J. Extramedullary myeloma in an HIVseropositive subject. Literature review and report of an unusual case. Head Face Med. 2009; 5(1). Article number 4. doi: 10.1186/1746-160X-5-4

2. Pantanowitz L., Dezube B.J. Editorial comments. Multiple myeloma and HIV infection- causal or causal to incidence? AIDS Read. 2003, 13(8): 386–7.

3. Pantanowitz L., Schlecht H.P., Dezube B.J. The growing problem of non-AIDS-defining malignancies in HIV. Curr. Opin. Oncol. 2006; 18: 469–78. DOI: 10.1097/01.cco.0000239886.13537.ed

4. Salarieh A., Rao C., Gottesman S.R.S., Alagha O., Todor R., Axiotis C.A. Plasma cell tumours in HIV-positive patients: report of a case and review of the literature. Leuk Lymphoma 2005, 46: 1067–74. DOI: 10.1080/10428190500054566

5. Лейгтон Р.А., Пивник А.В., Сергеева Е.П., Кремнева Н.В., Мухин О.В. Плазмоклеточные опухоли у ВИЧ-инфицированных пациентов (обзор литературы и собственные наблюдения). Клиническая онкогематология 2017; 10(4): 464–701. doi: 10.21320/2500-2139-2017-10-4-464-470

Leigton R.A., Pivnik A.V., Sergeeva E.P., Kremneva N.V., Mukhin O.V. [Plasma cell neoplasms in HIV-Infected Patients: A Literature Review and Case Series]. Clinical Оncohematology 2017; 10(4): 464–701. (In Russ.). doi: 10.21320/2500-2139-2017-10-4-464-470

6. Фалалеева Н.А., Терехова А.Ю., Птушкин В.В., Османов Е.А., Поддубная И.В., Невольских А.А. и др. Солитарная (экстрамедулярная) плазмоцитома. Клинические рекомендации. Современная онкология 2020; 22(1): 7–15. doi: 10.26442/18151434.2020.1.200048

Falaleeva N.A., Terekhova A.Iu., Ptushkin V.V., Osmanov E.A., Poddubnaya I.V. et al. [Solitary (extramedullary) plasmocytoma. Clinical recommendations]. Journal of Modern Oncology 2020; 22(1): 7–15. (In Russ.). doi: 10.26442/18151434.2020.1.200048

About the Authors

Naylia R. Мikhaylova, Cand. Med. Sci., Associate Professor, Department of epidemiology and infectious diseases, Orenburg State Medical University, Ministry of Health of the Russian Federation, Orenburg, Russia; n.mikhaylova@list.ru; http://orcid.org/- 0009-0006-7350-544X
Alekseу M. Mikhailovskу, MD, Сhief Medical Officer, Orenburg Regional Clinical Tuberculosis Dispensary, Orenburg, Russia; michailovsky2007@yandex.ru; http://orcid.org/-0000-0001-8995-9063
Oksana N. Plastamak, Phthisiatrician, Head, «Orenburgsky» branch department № 1, Orenburg Regional Clinical Tuberculosis Dispensary, Orenburg, Russia; plastamak123@mail.ru; http://orcid.org/-0009-0004-7181-8974
Tatiana N. Kalinina, Cand. Med. Sci., Associate Professor, Department of Epidemiology and Infectious Diseases, Orenburg State Medical University, Ministry of Health of Russian Federation, Orenburg, Russia; tkalinina31@gmail.com; http://orcid.org/-0009-0001-2737-9634
Natalya I. Skorovarova, Deputy Chief Physician for Treatment, Orenburg Regional Clinical Tuberculosis Dispensary, Orenburg, Russia, nataliskor@mail.ru, http://orcid.org/- 0009-0000-1240-7957
Olga V. Nuriachmetova, Cand. Med .Sci., Associate Professor, Department of Еpidemiology and Infectious Diseases, Orenburg State Medical University, Ministry of Health of Russian Federation, Orenburg, Russia; knjazkinaolja@mail.ru; http://orcid.org/-0009-0008-2147-5343
Tatiana N. Ermak, MD, Leading Research, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russia; t.ermak@hiv-russia.ru; http://orcid.org/-0000-0001-9490-7129

Similar Articles

By continuing to use our site, you consent to the processing of cookies that ensure the proper functioning of the site.